Table of Contents

1. Introduction
2. Description of HBsAg Rapid Test
3. Parameters and Procedures
4. Clinical Utility
5. Company Solutions
6. References

Introduction

The hepatitis B surface antigen (HBsAg) rapid test is a crucial tool in the detection and management of Hepatitis B virus (HBV) infections. It is designed to provide quick and reliable results, aiding healthcare providers in timely decision-making.

Description of HBsAg Rapid Test

The HBsAg rapid test is utilized to qualitatively detect the presence of Hepatitis B surface antigen in human serum, plasma, or whole blood. This test is especially significant in areas with high HBV prevalence and in settings where laboratory infrastructure is limited.

Parameters and Procedures

The HBsAg rapid test is characterized by its ease of use and rapid turnaround time. Typical sensitivity ranges from 90-100%, while specificity ranges from 95-100%. The procedure generally involves the following steps:

1. Collection of sample (serum, plasma, or whole blood).
2. Application of sample to the test device.
3. Waiting period of 15-20 minutes for result development.
4. Interpretation of results: one line indicating a non-reactive test and two lines indicating a reactive test.

Clinical Utility

This test serves as a crucial diagnostic tool in the following scenarios:

• Screening of blood donors to prevent transmission through transfusions.
• Diagnosis of acute or chronic HBV infection.
• Monitoring of patients undergoing treatment for HBV.

By swiftly identifying infected individuals, the HBsAg rapid test aids in preventing the spread of HBV and contributes to public health efforts in managing and controlling outbreaks.

Company Solutions

Several companies provide HBsAg rapid test solutions with varying features and capabilities:

• Company A: Offers a test with 99% specificity, available with a compact kit for field use.
• Company B: Provides a digital reader to enhance the accuracy of result interpretation.
• Company C: Focuses on affordable pricing models for low-income regions, ensuring widespread access.

References

• Johnston, L. et al., Evaluation of the HBsAg Rapid Test: Sensitivity, Specificity, and Clinical Implications, Journal of Infectious Diseases, 2023.
• World Health Organization, Guidelines for the Screening, Care and Treatment of Persons with Hepatitis B Infection, WHO Press, 2022.
• Smith, T. et al., Advances in Rapid Diagnostic Testing for Hepatitis B, Diagnostic Innovations, 2021.